Applications of Antisense Therapies to Restenosis by Alan D. Simon M.D., Mark K. Warshofsky M.D. (auth.), LeRoy

By Alan D. Simon M.D., Mark K. Warshofsky M.D. (auth.), LeRoy E. Rabbani M.D. (eds.)

Restenosis, the proliferation of soft muscle cells (SMC) that line blood vessels, usually follows angioplasty. regardless of advances in cardiology, restenosis maintains to impact as much as forty% of the over 500,000 sufferers who endure angioplasty every year.
Applications of Antisense remedies to Restenosis is the 1st quantity to deal with the possibility of utilizing antisense cures to inhibit the restenosis that happens after percutaneous transluminal angioplasty and coronary stenting. The paintings significantly examines the appliance of varied antisense remedies for inhibiting restenosis.

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell, 1991;64:1057. 'II. Involvement ofNF-kappa B activation in thrombin-induced human vascular smooth muscle cell proliferation. Biochem Biophys Res Commun, 1994;204:950. 'II. Thrombin receptor-mediated synovial proliferation in patients with rheumatoid arthritis. Clinic Immunollmmunopathol, 1995;76:225. Le Breton H, Plow EF, and Topol EJ. Role of platelets in restenosis after percutaneous coronary revascularization.

Arteritis in cardiac rejection after transplantation. Am J Cardiol,1987;59:1171. Zoja C, Furci L, Ghilardi F, et al. Cyclosporine-induced endothelial cell injury. Lab Invest, 1986;55:455. Salas E, Amado JA, Sanchez de Vega MJ, et al. Impaired vascular smooth muscle nitric oxidedependent relaxation in human coronary arteries from "transplanted heart vasculopathy". Arch 1~1 Cardiol Mex, 1997;67(1):11. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990's. 801. Johnson DE, Hinohara T, Selman MR, et al.

WB Saunders Company, Philadelphia, Pa; 1994. Nobuyushi M, Kimura T, Nosaka H, et a!. Restenosis after successful coronary angioplasty: serial angiographic follow-up of229 patients. J Am Coli Cardiol, 1988;12:616. Chesebro m, Web~1er MWl, Reeder GS, et a!. Coronary angioplasty: antiplatelet therapy reduces acute complications, but not re~1enosis (ab~1ract). Circulation, 1989;80(suppI2):64. Holmes DR, Vliestra RE, Smith HC, et a!. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): A report from the PTCA registry of the National Heart, Lung, and Blood Institute.

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