Advances in Cardiomyopathies: Proceedings of the II Florence by J. F. Goodwin (auth.), Fulvio Camerini, Antonello Gavazzi,

By J. F. Goodwin (auth.), Fulvio Camerini, Antonello Gavazzi, Renata De Maria (eds.)

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Increased extravascular resistance). g. endothelin, neuropeptide Y, serotonin). In addition, the small coronary arterioles receive autonomic innervation and their diameter may be altered by stimulation of these nerves [16]. 2- Remodelling of the Vessel Wall The structural remodelling of the coronary microcirculation, as that observed in hypertensive heart disease [17-19] and HeM [6], includes changes in the arteriolar wall and a relative reduction in the total number of vessels, probably as a consequence of the disproportionate growth of myocytes, without a corresponding increase in the available blood supply.

Hoffman JI (1987) Transmural myocardial perfusion. Progress in Cardiovascular Diseases XXIX:429-464 16. De Silva R, Camici PG (1994) Role of positron emission tomography in the investigation of human coronary circulatory function. Cardiovasc Res 28:1595-1612 17. Strauer BE, Schwartzkopff B, Motz W, Vogt M (1991) Coronary vascular changes in the progression and regression of hypertensive heart disease. J Cardiovasc Pharmacol 18 [Suppl 3]: S20-7 18. Schwartzopff B, Motz W, Frenzel H, Vogt M, Knauer S, Strauer E (1993) Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension.

Camici PG, Cecchi F, Gistri R, Montereggi A, Salvadori P, Dolara A, L' Abbate A (1991) Dipyridamole-induced subendocardial underperfusion in hypertrophic cardiomyopathy assessed by positron-emission tomography. Coronary Artery Disease 2:837841 13. Gistri R, Cecchi F, Choudhury L, Montereggi A, Sorace 0, Salvadori PA, Camici PG (1994) Effect of verapamil treatment on absolute myocardial blood flow in hypertrophic cardiomyopathy. Am J Cardiol 74:363-368 14. Choudhury L, Ryan MP, Page CA, Boyd H, Elliott P, McKenna WJ, Camici PG (1994) Does verapamil favourably alter transmural myocardial blood flow distribution in hypertrophic cardiomyopathy?

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