Acute Respiratory Distress Syndrome, Second Edition, Volume by Augustine M. K. Choi

By Augustine M. K. Choi

The one on hand textual content to concentration totally on Acute breathing misery Syndrome (ARDS). completely revised content material and ten new chapters offer pulmonologists with the newest advancements and functions of pharmacological and mechanical treatments had to deal with the debilitating and hard of ARDS. Highlights comprise: the definition, epidemiology, pathology, and pathogenesis of ARDS issues akin to transfusion-related damage, and endothelium and vascular disorder the long term results of ARDS host safety and an infection the most recent advancements in ARDS treatment: glucocorticoid treatment, surfactant remedy, mechanical air flow, and mesenchymal stem cells predictive components: gene expression profiling and biomarkers, and chemokines and cytokines advances in administration ideas: fluid administration, non-pulmonary and non-sepsis administration, and glucose keep an eye on

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Additional resources for Acute Respiratory Distress Syndrome, Second Edition, Volume 233 (Lung Biology in Health and Disease)

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For example, differences in smoking, use of motor vehicles, population density, incidence of respiratory infections, and genetic factors might all influence geographic variability in the incidence of ALI. An interesting and unexplored source of variation is the effect of health care resource use on ALI incidence. Even within the United States there is wide variability in the number of hospital beds and ICU beds, emergency medical response time, and other medical resources. These may influence the observed incidence of ALI in two ways.

Given the evidence of interobserver variability in clinician radiographic interpretation and diagnosis of ALI (5,6), rigorous protocolized case identification is necessary in epidemiological studies of ALI. True variability in incidence is a potential explanation of the existing studies. No single number reflects the incidence rate for myocardial infarction, colon cancer, or motor vehicle collisions, and we should not expect a single incidence figure for ALI. Potential explanations for this variability include differences in the incidence of risk factors, susceptibility (including genetic variation), and health care utilization.

Another study exploring the influence of race and ethnicity on mortality found that black and Hispanic patients with ALI had a significantly higher risk of death compared to white patients (33). One of the surprising observations from recent epidemiological studies in ALI is the similar mortality, approximately 40%, that exists among the following different categories of respiratory failure: (1) patients with ARDS, (2) patients with ALI who meet other criteria for ARDS but with less severe hypoxemia (200 Ͻ Pao2 /Fio2 Ͻ 300), and (3) patients with acute respiratory failure (intubation and mechanical ventilation Ͼ24 hours regardless of etiology, radiograph, or degree of hypoxemia) (26,34).

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